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UniProtKB/Swiss-Prot entry B0CK15


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PNP_BRUSI
Primary accession number B0CK15
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on February 26, 2008 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 8)
Name and origin of the protein
Protein name Polyribonucleotide nucleotidyltransferase
Synonyms EC 2.7.7.8
Polynucleotide phosphorylase
PNPase
Gene name
Name: pnp
OrderedLocusNames: BSUIS_A2006
From
Brucella suis (strain ATCC 23445 / NCTC 10510) [TaxID: 470137] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S.;
"Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000911; ABY39016.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001628587.1; -.
3D structure databases
ModBase B0CK15.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0000175; Molecular function: 3'-5'-exoribonuclease activity (inferred from electronic annotation from InterPro).
GO:0004654; Molecular function: polyribonucleotide nucleotidyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0003723; Molecular function: RNA binding (inferred from electronic annotation from InterPro).
GO:0006402; Biological process: mRNA catabolic process (inferred from electronic annotation from HAMAP).
GO:0006396; Biological process: RNA processing (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_01595; -; 1.
PBIL [Tree]
InterPro IPR004087; KH.
IPR004088; KH_type_1.
IPR012340; NA-bd_OB-fold.
IPR012162; PNPase.
IPR015848; PNPase_PH_RNA-bd_bac/org-type.
IPR003029; S1_RNA-bd.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
G3DSA:1.10.10.400; PNPase_PH_RNA-bd_bac/org-type; 1.
PANTHER PTHR11252; PNPase; 1.
PIRSF PIRSF005499; PNPase; 1.
SMART SM00322; KH; 1.
SM00316; S1; 1.
SMART graphical view of domain structure.
PROSITE PS50084; KH_TYPE_1; 1.
PS50126; S1; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 5838194; -.
GenomeReviews CP000911_GR; BSUIS_A2006.
KEGG bmt:BSUIS_A2006; -.
CMR B0CK15; BSUIS_A2006.
Other
ProtoNet B0CK15.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Nucleotidyltransferase; RNA-binding; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   714  714     Polyribonucleotide nucleotidyltransferase. PRO_1000087985
DOMAIN   555   614  60     KH. 
DOMAIN   624   692  69     S1 motif. 
Sequence information
Length: 714 AA [This is the length of the unprocessed precursor] Molecular weight: 77730 Da [This is the MW of the unprocessed precursor] CRC64: 61E6696AD66B29F7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFNTHKVEIE WGGRPLTLET GKIARQADGA VLATYGETAV LATVVSAKEP KPGQDFFPLT 

        70         80         90        100        110        120 
VNYQEKTYAA GKIPGGYFKR EGRPSENETL VSRLIDRPIR PLFVDGYKND TQVVITVLQH 

       130        140        150        160        170        180 
DLENNPDILS MVAASAALTI SGVPFMGPIS GARVGYIDGE YVLNPNIDEM PESKLDLVVA 

       190        200        210        220        230        240 
GTSEAVLMVE SEAQELPEDV MLGAVMFGHK SFQPVIDAII KLAEVAAKEP RDFQPEDLSE 

       250        260        270        280        290        300 
LEAKVLAVVE NDLREAYKIT EKQARYAAVD AAKAKAKEHF FPEGVEETEM SAEQFATIFK 

       310        320        330        340        350        360 
HLQAKIVRWN ILDTGNRIDG RDLSTVRPIV SEVGILPRTH GSALFTRGET QAIVVATLGT 

       370        380        390        400        410        420 
GEDEQMIDAL TGTYKESFML HYNFPPYSVG ETGRMGSPGR REIGHGKLAW RAIHPMLPAA 

       430        440        450        460        470        480 
EQFPYTIRAV SEITESNGSS SMATVCGTSL ALMDAGVPIV RPVAGIAMGL IKEGERFAVL 

       490        500        510        520        530        540 
SDILGDEDHL GDMDFKVAGT EFGITSLQMD IKIDGITEEI MKVALEQAKG GRVHILGEMA 

       550        560        570        580        590        600 
KAISSSRAEL GEFAPRIEVM NIPTDKIRDV IGSGGKVIRE IVEKTGAKIN IEDDGTVKIA 

       610        620        630        640        650        660 
SSNGKEIEAA KKWIHSIVAE PEVGEIYEGT VVKTADFGAF VNFFGPRDGL VHISQLAADR 

       670        680        690        700        710 
VAKTTDVVKE GQKVWVKLMG FDERGKVRLS MKVVDQETGK EIVAEKKKEE VDAE 

B0CK15 in FASTA format

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