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UniProtKB/Swiss-Prot entry A7THS1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MCR1A_VANPO
Primary accession number A7THS1
Secondary accession numbers None
Integrated into Swiss-Prot on April 29, 2008
Sequence was last modified on October 2, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 13)
Name and origin of the protein
Protein name NADH-cytochrome b5 reductase 2-A
Synonyms EC 1.6.2.2
Mitochondrial cytochrome b reductase A
Gene name
Name: MCR1A
ORFNames: Kpol_543p67
From
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus) [TaxID: 436907] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0608218104; PubMed=17494770 [NCBI, ExPASy, EBI, Israel, Japan]
Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
"Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication.";
Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
DS480392; EDO18237.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001646095.1; -.
3D structure databases
ModBase A7THS1.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005741; Cellular component: mitochondrial outer membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0004128; Molecular function: cytochrome-b5 reductase activity (inferred from electronic annotation from EC).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001834; Cyt_B5_reductase.
IPR001709; FPN_cyt_redctse.
IPR008333; OxRdtase_FAD-bd.
IPR001433; OxRdtase_FAD/NAD_bd.
Graphical view of domain structure.
Pfam PF00970; FAD_binding_6; 1.
PF00175; NAD_binding_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00406; CYTB5RDTASE.
PR00371; FPNCR.
PROSITE PS51384; FAD_FR; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 5546512; -.
KEGG vpo:Kpol_543p67; -.
Other
ProtoNet A7THS1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion outer membrane; NAD; Oxidoreductase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   296  296     NADH-cytochrome b5 reductase 2-A. PRO_0000330192
TRANSMEM   15    35  21     Potential. 
DOMAIN   47   151  105     FAD-binding FR-type. 
NP_BIND   154   189  36     FAD (By similarity). 
Sequence information
Length: 296 AA [This is the length of the unprocessed precursor] Molecular weight: 33138 Da [This is the MW of the unprocessed precursor] CRC64: BF0E67ABEBB14308 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MFARIARINP KILPFVIGAP TIALCSYYYS SGAFLRNESS KVFIGDNNWI DLPISRIEEI 

        70         80         90        100        110        120 
SHDTKRFTFK YPSQDSVSGL VVASALLTKF VTPKGSNVIR PYTPVSDVDE KGSLDLVIKH 

       130        140        150        160        170        180 
YPDGKMTNHI FSLKVNDTLS FKGPIPKWKW VPNSFESITL IGGGTGITPL YQLIHAITKN 

       190        200        210        220        230        240 
PNDKTKIRLF YSNKTSQDVL MKKELDELQA KYPDQLRITY FITTPDKGYK GESGFISKEF 

       250        260        270        280        290 
IASNADKPSP KSHVFVCGPP PFMNAYSGDK KSPTDQGELV GILKELGYTI DQVYKF
A7THS1 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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