NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Wang S.Y., Zheng H.J., Lv L.D., Wang B.F., Zhang X.L., Pu S.Y., Zhu G.F., Wang H.H., Zhao G.P., Zhang Y.;
"Complete genomic sequence of Mycobacterium tuberculosis strain H37Ra, a non-pathogenic variant closely related to the well-characterized pathogenic strain H37Rv.";
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: (S)-malate + acceptor = oxaloacetate + reduced acceptor.
COFACTOR: FAD (By similarity).
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle .
SIMILARITY: Belongs to the MQO family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000611; ABQ74654.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001284216.1; -.

3D structure databases

ModBase

A5U6K4.

Ontologies

GO:0008924;	Molecular function: malate dehydrogenase (acceptor) activity (inferred from electronic annotation from HAMAP).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006099;	Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00212; -; 1.
PBIL [Tree]

InterPro

IPR006231; Malate_quinone_OxRdtase.
Graphical view of domain structure.

Pfam

PF06039; Mqo; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR01320; mal_quin_oxido; 1.

Genome annotation databases

GeneID

5212407; -.

GenomeReviews

CP000611_GR; MRA_2875.

KEGG

mra:MRA_2875; -.

CMR

A5U6K4; MRA_2875.

Other

ProtoNet

A5U6K4.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 493`	`493`		`Probable malate:quinone oxidoreductase.`	`PRO_1000023808`

Sequence information

Length: 493 AA [This is the length of the unprocessed precursor]

Molecular weight: 53595 Da [This is the MW of the unprocessed precursor]

CRC64: C3B4C469FF4F285F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSDLARTDVV LIGAGIMSAT LGVLLRRLEP NWSITLIERL DAVAAESSGP WNNAGTGHSA 

        70         80         90        100        110        120 
LCEMNYTPEM PDGSIDITKA VRVNEQFQVT RQFWAYAAEN GILTDVRSFL NPVPHVSFVH 

       130        140        150        160        170        180 
GSRGVEYLRR RQKALAGNPL FAGTEFIESP DEFARRLPFM AAKRAFSEPV ALNWAADGTD 

       190        200        210        220        230        240 
VDFGALAKQL IGYCVQNGTT ALFGHEVRNL SRQSDGSWTV TMCNRRTGEK RKLNTKFVFV 

       250        260        270        280        290        300 
GAGGDTLPVL QKSGIKEVKG FAGFPIGGRF LRAGNPALTA SHRAKVYGFP APGAPPLGAL 

       310        320        330        340        350        360 
HLDLRFVNGK SWLVFGPYAG WSPKFLKHGQ ISDLPRSIRP DNLLSVLGVG LTERRLLNYL 

       370        380        390        400        410        420 
ISQLRLSEPE RVSALREFAP SAIDSDWELT IAGQRVQVIR RDERNGGVLE FGTTVIGDAD 

       430        440        450        460        470        480 
GSIAGLLGGS PGASTAVAIM LDVLQKCFAN RYQSWLPTLK EMVPSLGVQL SNEPALFDEV 

       490 
WSWSTKALKL GAA

A5U6K4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools