ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry A5FRZ5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name AROE_DEHSB
Primary accession number A5FRZ5
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on June 12, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 19)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: DehaBAV1_0442
From
Dehalococcoides sp. (strain BAV1) [TaxID: 216389] [HAMAP proteome]
Taxonomy Bacteria; Chloroflexi; Dehalococcoidetes; Dehalococcoides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ritalahti K.M., Loeffler F., Richardson P.;
"Complete sequence of Dehalococcoides sp. BAV1.";
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000688; ABQ17027.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001213905.1; -.
3D structure databases
ModBase A5FRZ5.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
Genome annotation databases
GeneID 5131197; -.
GenomeReviews CP000688_GR; DehaBAV1_0442.
KEGG deb:DehaBAV1_0442; -.
CMR A5FRZ5; DehaBAV1_0442.
Other
ProtoNet A5FRZ5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   286  286     Shikimate dehydrogenase. PRO_1000078119
NP_BIND   130   134  5     NADP (By similarity). 
ACT_SITE   70    70        Proton acceptor (Potential). 
Sequence information
Length: 286 AA [This is the length of the unprocessed precursor] Molecular weight: 31321 Da [This is the MW of the unprocessed precursor] CRC64: E42021D763509617 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQTIPDALFG IIGYPVSHSV SPAMQNAAFK HCKLNYLYLT IAAKPEDLQN VIASMRPLNI 

        70         80         90        100        110        120 
RGLNVTIPHK IEVIKYIDTL DPAAKKIGAV NTIVNENGQM KGYNTDFGGF VRLLEHNRIA 

       130        140        150        160        170        180 
PAKHRFALLG AGGSAHAISL AICTLGGHLT VLARQEEKAK DLAAKMCLRF KGKAQGLELN 

       190        200        210        220        230        240 
EANLEETLAE SDIIVNCTPI GMGNLAGQSL ISPRLLRPDL TVIDAIYNPC KTRLLEDAEK 

       250        260        270        280 
KGAKIINGLE MLVWQGAMSF EIWTSQKAPF RVMMKEAEMA LDENEK
A5FRZ5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!