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UniProtKB/Swiss-Prot entry A4YRD9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNAE2_BRASO
Primary accession number A4YRD9
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on May 29, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 12)
Name and origin of the protein
Protein name Error-prone DNA polymerase
Synonym EC 2.7.7.7
Gene name
Name: dnaE2
OrderedLocusNames: BRADO2647
From
Bradyrhizobium sp. (strain ORS278) [TaxID: 114615] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1139548; PubMed=17540897 [NCBI, ExPASy, EBI, Israel, Japan]
Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z., Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
Science 316:1307-1312(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU234118; CAL76465.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001204702.1; -.
3D structure databases
ModBase A4YRD9.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008408; Molecular function: 3'-5' exonuclease activity (inferred from electronic annotation from InterPro).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0003887; Molecular function: DNA-directed DNA polymerase activity (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from InterPro).
GO:0045020; Biological process: error-prone DNA repair (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01902; -; 1.
PBIL [Tree]
InterPro IPR011708; DNA_pol3_alpha.
IPR012340; NA-bd_OB-fold.
IPR004365; NA_bd_OB_tRNA-helicase.
IPR004013; PHP_C.
IPR003141; PHP_N.
IPR004805; PolC_alpha.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
Pfam PF07733; DNA_pol3_alpha; 1.
PF02811; PHP; 1.
PF01336; tRNA_anti; 1.
Pfam graphical view of domain structure.
SMART SM00481; POLIIIAc; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00594; polc; 1.
Genome annotation databases
GeneID 5120654; -.
GenomeReviews CU234118_GR; BRADO2647.
KEGG bra:BRADO2647; -.
CMR A4YRD9; BRADO2647.
Other
ProtoNet A4YRD9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   1170  1170     Error-prone DNA polymerase. PRO_1000070589
Sequence information
Length: 1170 AA [This is the length of the unprocessed precursor] Molecular weight: 131983 Da [This is the MW of the unprocessed precursor] CRC64: 73C24A0B6EA41E32 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTPIPYAEIG VTTNFSFLHG GSHPQAYVHQ AAEYGLTAIG IADHNTLAGI VRAYSELSND 

        70         80         90        100        110        120 
QLGYRPKLLY GARLVFTCGT PDILVYPRDR AAYGRLCQLL TRGKRGSDLD KVAKGDCRLA 

       130        140        150        160        170        180 
FEDLFDFIAG QLLVLMPPHR FDEDALGAIL ARLKDSPAEG VWLAGSLLYR GDDRRRLARL 

       190        200        210        220        230        240 
ARLAASAKVP LIATNDVLYH HPQQRMLQDV LTCIREKASI ESIGRRLQAN AERHLKPGHE 

       250        260        270        280        290        300 
MARLFRDHPE AIAETLRFTD RIVFSLDQLK YQYPDEPVPP GKTAQGHLED LTWAGAKTYF 

       310        320        330        340        350        360 
GDKLDDRLRA VLNKELALIA ELNYAHYFLT VHDIVRYARS EGILCQGRGS AANSAVCYVL 

       370        380        390        400        410        420 
GITSVDPTKI DLLFERFISK ERLEPPDIDV DFEHSRREEV MQYVYHRYGR HRAAIIATVI 

       430        440        450        460        470        480 
HYRPRSAIRD VGKALGLTED VTSVLADTVW GSWGDGLSDM QVRQAGLDPH NPMIRRAVEL 

       490        500        510        520        530        540 
ASELITFPRH LSQHVGGYVL TQDRLDSYVP IGNAAMDDRT FIEWDKDDVD ALSMMKVDVL 

       550        560        570        580        590        600 
ALGMLTCIRK SFDLIADHKG RRYVLSDIKS EDDNEVYQML QRGESLGVFQ VESRAQMNML 

       610        620        630        640        650        660 
PRLKPRTFYD LVIEVAIVRP GPIQGDMVHP YLRRRNKLEK VTYPSPSPDH GPSDELYKVL 

       670        680        690        700        710        720 
HKTLGVPLFQ EQAMRIAIEA AKFSPEEANG LRRAMATFRN VGTIGSYEEK MVSNMIARGY 

       730        740        750        760        770        780 
DPAFAKSCFD QIKGFGSYGF PESHAASFAQ LVYVSSWLKY FHPDAFCCAL LNSQPMGFYA 

       790        800        810        820        830        840 
PAQIVGDARK NGVEIRDIDV SHSFADNTLE KTDGEYCAVR LGFRQIDGFR WIDRDEERIR 

       850        860        870        880        890        900 
KLSEAVRKEA LSVSTRSLPA ISPVSFRGAR SANPESRDSG FALRAPRNDN DRQIPLHNDD 

       910        920        930        940        950        960 
REDDWADRII RARQRRPFTS LEDFARDTAL PKRALLLLAD ADAFRSLGLD RRAALWAVRR 

       970        980        990       1000       1010       1020 
LPDDVPLPLF EAAIAREQPD EGAQPLPEMP LPEHVVADYQ TIRLSLKGHP MEFLRRRFAA 

      1030       1040       1050       1060       1070       1080 
EGVLACRDVN DTNDRRRIRC AGVVLVRQRP GSAKGVVFMT LEDETGIANI VVWPKVMETF 

      1090       1100       1110       1120       1130       1140 
RKEVMGARLV LVEGRIQSSP EKVVHLVAER LVDRTADLTL LSDDRLDAIP HGATPAEPLN 

      1150       1160       1170 
DDRRDHTDNP SQRVSHPRNV RILPRSRDFH 

A4YRD9 in FASTA format

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