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UniProtKB/Swiss-Prot entry A4YHA5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P_METS5
Primary accession number A4YHA5
Secondary accession numbers None
Integrated into Swiss-Prot on February 26, 2008
Sequence was last modified on May 29, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 14)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
OrderedLocusNames: Msed_1652
From
Metallosphaera sedula (strain ATCC 51363 / DSM 5348) [TaxID: 399549] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Metallosphaera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Han C., Detter J.C., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Maezato Y., Auernik K.S., Kelly R.M., Blum P., Richardson P.;
"Complete sequence of Metallosphaera sedula DSM 5348.";
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000682; ABP95807.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001191731.1; -.
3D structure databases
ModBase A4YHA5.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0043891; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity (inferred from electronic annotation from EC).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
Genome annotation databases
GeneID 5104857; -.
GenomeReviews CP000682_GR; Msed_1652.
KEGG mse:Msed_1652; -.
CMR A4YHA5; Msed_1652.
Other
ProtoNet A4YHA5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   340  340     Glyceraldehyde-3-phosphate dehydrogenase. PRO_1000072562
NP_BIND   11    12  2     NAD (By similarity). 
REGION   138   140  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   193   194  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   139   139        Nucleophile (By similarity). 
BINDING   109   109        NAD; via amide nitrogen (By similarity). 
BINDING   167   167        NAD (By similarity). 
BINDING   300   300        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 340 AA [This is the length of the unprocessed precursor] Molecular weight: 36648 Da [This is the MW of the unprocessed precursor] CRC64: 997600B78F9101A1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIKVAVNGYG TIGKRVASAI LAQPDMTLVG VSKTSPNYEA YQAQKMGINL YVTKESLKEF 

        70         80         90        100        110        120 
EEAGIKVKGV LEDMIKEADV VVDATPNGVG AQYKQVYSSM GKRALFQGGE KANVADVSFS 

       130        140        150        160        170        180 
ALCNYDEAVD KRYVRVVSCN TTGLLRTLCT LNRVSKIAKV RGTIVRRAAD PKEVKKGPIN 

       190        200        210        220        230        240 
SLVPDPASIP SHHAKDVNTV LKDLDIVTMA VVAPTTLMHV HLLDVTVSSP VTKEDVLSVL 

       250        260        270        280        290        300 
SSTPRILLAS GKSKVSSTAE IVEVARDMGR PRNDLYELVV FEDSVSVRGN EVFLMYAVHQ 

       310        320        330        340 
ESIVVPENVD AIRAVSGFAD GRKSIEMTNA SMGIGKGYLV
A4YHA5 in FASTA format

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