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UniProtKB/Swiss-Prot entry A4WIW2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P_PYRAR
Primary accession number A4WIW2
Secondary accession numbers None
Integrated into Swiss-Prot on September 11, 2007
Sequence was last modified on May 29, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 14)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
OrderedLocusNames: Pars_0743
From
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321) [TaxID: 340102] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Cozen A.E., Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.;
"Complete sequence of Pyrobaculum arsenaticum DSM 13514.";
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000660; ABP50329.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001152981.1; -.
3D structure databases
ModBase A4WIW2.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0043891; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity (inferred from electronic annotation from EC).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
Genome annotation databases
GeneID 5054487; -.
GenomeReviews CP000660_GR; Pars_0743.
KEGG pas:Pars_0743; -.
CMR A4WIW2; Pars_0743.
Other
ProtoNet A4WIW2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   344  344     Glyceraldehyde-3-phosphate dehydrogenase. PRO_0000300975
NP_BIND   11    12  2     NAD (By similarity). 
REGION   139   141  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   195   196  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   140   140        Nucleophile (By similarity). 
BINDING   110   110        NAD; via amide nitrogen (By similarity). 
BINDING   169   169        NAD (By similarity). 
BINDING   302   302        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 344 AA [This is the length of the unprocessed precursor] Molecular weight: 37492 Da [This is the MW of the unprocessed precursor] CRC64: 02B316F2B8F47E36 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIRVGIVGFG TIGKRIADAV AAQGDMHVSG VLKVTPDYEV LVAAAKGFKV YTLPDRVEKF 

        70         80         90        100        110        120 
KKAGIEPAGT IEDLIKASDV IIDASPEDVG AENKEKYYSK FDKPVIFQGG EEAEVAEVSF 

       130        140        150        160        170        180 
NALANYDEAR GRRYVRVVSC NTTGITRVLT SLMLNGVGIK KARIFIARRG ADPKEYKKGP 

       190        200        210        220        230        240 
INDVVPNPAT VPSHHGPDVK TVLKNVDIVT MAVAVPVTIM HMHMAFLELD GAYPRDAVLE 

       250        260        270        280        290        300 
ALAKTPRIFL ADVGAGFQSL AQIIEYARDL GRPRGDFPEV AIFRDSVTVN GNELYLMYGV 

       310        320        330        340 
HQESIVVPEN VDAVRAVLGA MPKWESIKKT DTTLKLFTEG KRYG
A4WIW2 in FASTA format

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