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UniProtKB/Swiss-Prot entry A4IJP9

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ROCA_GEOTN
Primary accession number A4IJP9
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on May 1, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 16)
Name and origin of the protein
Protein name 1-pyrroline-5-carboxylate dehydrogenase
Synonyms P5C dehydrogenase
EC 1.5.1.12
Gene name
Name: rocA
OrderedLocusNames: GTNG_0169
From
Geobacillus thermodenitrificans (strain NG80-2) [TaxID: 420246] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Geobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0609650104; PubMed=17372208 [NCBI, ExPASy, EBI, Israel, Japan]
Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L.;
"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.";
Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000557; ABO65553.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001124298.1; -.
3D structure databases
ModBase A4IJP9.
Ontologies
GO
GO:0003842; Molecular function: 1-pyrroline-5-carboxylate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006537; Biological process: glutamate biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00733; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR005932; d-1-pyrroline-5-COlate_DHase-2.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01237; D1pyr5carbox2; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
Genome annotation databases
GeneID 4965022; -.
GenomeReviews CP000557_GR; GTNG_0169.
KEGG gtn:GTNG_0169; -.
NMPDR fig|420246.5.peg.171; -.
CMR A4IJP9; GTNG_0169.
Other
ProtoNet A4IJP9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   515  515     1-pyrroline-5-carboxylate dehydrogenase. PRO_1000045971
ACT_SITE   286   286        By similarity. 
ACT_SITE   320   320        By similarity. 
Sequence information
Length: 515 AA [This is the length of the unprocessed precursor] Molecular weight: 56574 Da [This is the MW of the unprocessed precursor] CRC64: 07C58FFA56B656FD [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVQPYKHEPF TDFTVDANRQ AFLAALEKVE AELGREYPLI IGGERVMTED KITSVNPANK 

        70         80         90        100        110        120 
AEVIGRVAKA NKELAERAMK TADEAFRTWS RTSPEARADI LFRAAAIVRR RKHEFSAWLV 

       130        140        150        160        170        180 
KEAGKPWREA DADTAEAIDF MEYYGRQMLK LKDGIPVESR PGETNRFFYI PLGVGVVISP 

       190        200        210        220        230        240 
WNFPFAIMAG TTVAALVTGN TVLLKPASAT PVVAYKFAEV LEEAGLPAGV LNYIPGSGAE 

       250        260        270        280        290        300 
VGDYLVEHPR TRFISFTGSR DVGIRIYERA AKVQPGQIWL KRVIAEMGGK DAIVVDKEAD 

       310        320        330        340        350        360 
LELAAQSIVA SAFGFSGQKC SACSRAIIVE DVYDQVLNRV VELTKQLNVG DPAEQATFMG 

       370        380        390        400        410        420 
PVIDQGAYNK IMEYIEIGKQ EGRLMTGGEG DDSKGFFIQP TVFADVDPNA RIMQEEIFGP 

       430        440        450        460        470        480 
VVAFAKARDF DHALEIANNT QYGLTGAVIS RNRANLEKAR HEFHVGNLYF NRGCTGAIVG 

       490        500        510 
YQPFGGFNMS GTDSKAGGPD YLILHMQAKT VSEMF
A4IJP9 in FASTA format

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