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UniProtKB/Swiss-Prot entry A2QIL5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ATG1_ASPNC
Primary accession number A2QIL5
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on March 6, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 16)
Name and origin of the protein
Protein name Serine/threonine-protein kinase atg1
Synonyms EC 2.7.11.1
Autophagy-related protein 1
Gene name
Name: atg1
ORFNames: An04g03950
From
Aspergillus niger (strain CBS 513.88 / FGSC A1513) [TaxID: 425011] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1282; PubMed=17259976 [NCBI, ExPASy, EBI, Israel, Japan]
Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
"Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88.";
Nat. Biotechnol. 25:221-231(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM270075; CAK38659.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001401761.1; -.
3D structure databases
ModBase A2QIL5.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0004674; Molecular function: protein serine/threonine kinase activity (inferred from electronic annotation from InterPro).
GO:0006914; Biological process: autophagy (inferred from electronic annotation from UniProtKB-KW).
GO:0006468; Biological process: protein amino acid phosphorylation (inferred from electronic annotation from InterPro).
GO:0015031; Biological process: protein transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000719; Prot_kinase_core.
IPR017441; Protein_kinase_ATP_bd_CS.
IPR017442; Se/Thr_pkinase-rel.
IPR008271; Ser_thr_pkin_AS.
IPR002290; Ser_thr_pkinase.
Graphical view of domain structure.
Pfam PF00069; Pkinase; 1.
Pfam graphical view of domain structure.
ProDom PD000001; Prot_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00220; S_TKc; 1.
SMART graphical view of domain structure.
PROSITE PS00107; PROTEIN_KINASE_ATP; 1.
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet A2QIL5.
Genome annotation databases
GeneID 4990801; -.
KEGG ang:An04g03950; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Autophagy; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Protein transport; Serine/threonine-protein kinase; Transferase; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   1007  1007     Serine/threonine-protein kinase atg1. PRO_0000317788
DOMAIN   30    336  307     Protein kinase. 
NP_BIND   36     44  9     ATP (By similarity). 
ACT_SITE   174    174        Proton acceptor (By similarity). 
BINDING   59     59        ATP (By similarity). 
Sequence information
Length: 1007 AA [This is the length of the unprocessed precursor] Molecular weight: 108897 Da [This is the MW of the unprocessed precursor] CRC64: D15EEE57D480DAFD [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGLFHHSTLF LPLLRRSNEG PHGEMPIGHY TRLSEIGRGS FAVVYKGVHT RSRTYVAIKS 

        70         80         90        100        110        120 
VTMTKLSRKL KENLASEISI LKQLHHPHIV ALLDCHDTTS NIHLVMEFCA LGDLSHFIKG 

       130        140        150        160        170        180 
RNTLQDSPYT RELIAKYPNP GEGAGLNEVI VRHFLKQLSS ALRFLRDRDL IHRDIKPQNL 

       190        200        210        220        230        240 
LLCPAPSSYR SGAADVVPFK SSEDSFSPKT GLESLPMLKL ADFGFARSLP ATSLAETLCG 

       250        260        270        280        290        300 
SPLYMAPEIL RYEKYDAKAD LWSVGTVLYE MVVGRAPFRA VNHIELIKKI EQNKDQISFP 

       310        320        330        340        350        360 
SKNRVSEDIR ELIRGLLKQH PMDRMNFDVY FAHKVLTEPI PGLVADDAPL GRSPADPTPR 

       370        380        390        400        410        420 
PGSGSRRSTP VQMKRENALS GGVRDEPATY PAAQRAMTQS PRPETPSTPM RRTGSAGTPH 

       430        440        450        460        470        480 
AAPNEPTPPA SHPTRPSPVS LATAPGRQEH VDRPPTTTVV EQQRRRTASS GVPQVDKPVE 

       490        500        510        520        530        540 
KAKDEKEHAA QEVAFERDYV LVEKRAVEMN AFADELAYNP RMQGGQAGAV SRRSGAAPGT 

       550        560        570        580        590        600 
PPAGGSSPHA SPSKAMQIIS GRSRADSAHV RQNSYDRRYG QSPTSATSAI SKALNMASGR 

       610        620        630        640        650        660 
LFGMSFSPPL TITKGGRSPP LAYNPFPAYP SAQTSLIVHA DGGKPGANLD EDSKTVHDLE 

       670        680        690        700        710        720 
ECATRSDVVY GFAEVKYKQL IPLAPSAATG YPGDPGSDAV DSADGGLTVD AIVTLSEEAL 

       730        740        750        760        770        780 
VLYVKALSLL AKSMDIARVW WTRKSRGDTL SRADTGSTVA GNRINNVVQW VRNRFNEVLE 

       790        800        810        820        830        840 
KAEFVRLKLV EAQKRLPSDH PSHPSNLSVG SSLGSGTSAD VVVSPDVTAE KLMYERALEM 

       850        860        870        880        890        900 
SRVAAINEIT GEDLAGCEIS YVTAIRMLEA ILDDVEVSRP GQSGGADRAD ARRDNEDGGQ 

       910        920        930        940        950        960 
NEPQAVILAK SANAWHSDIE NPESPGVAPE EAGAAVESVH APVQWTGQNA AVESGASLPC 

       970        980        990       1000 
SGSHAAEIRT LTVRSMQDHA HFAPLLFSIF ISSYSSSISC PSSCGHC 

A2QIL5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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