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UniProtKB/Swiss-Prot entry A1S9I4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_SHEAM
Primary accession number A1S9I4
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 17)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: Sama_2838
From
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) [TaxID: 326297] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P.;
"Complete sequence of Shewanella amazonensis SB2B.";
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000507; ABM01041.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_928710.1; -.
3D structure databases
ModBase A1S9I4.
Ontologies
GO
GO:0009337; Cellular component: sulfite reductase complex (NADPH) (inferred from electronic annotation from InterPro).
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0019344; Biological process: cysteine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; FALSE_NEG.
ProtoNet A1S9I4.
Genome annotation databases
GeneID 4605085; -.
GenomeReviews CP000507_GR; Sama_2838.
KEGG saz:Sama_2838; -.
NMPDR fig|326297.7.peg.2659; -.
CMR A1S9I4; Sama_2838.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   571  571     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000318562
METAL   435   435        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   441   441        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   480   480        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   484   484        Iron (siroheme axial ligand) (By similarity). 
METAL   484   484        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 571 AA [This is the length of the unprocessed precursor] Molecular weight: 63430 Da [This is the MW of the unprocessed precursor] CRC64: 99B82D9861DF90A7 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSQYPIKPEL QVQGQLSDNE RLKAESNHLR GTITTDLKDE ITGGFTGDNF MLVRFHGMYQ 

        70         80         90        100        110        120 
QDDRDLRAER AEQKLEPLHN VMLRARMPGG IIKPEQWLAI DEFAREHTMY GSIRLTTRQT 

       130        140        150        160        170        180 
FQFHGVFKPD IKPMHQMLNK IGIDSIATAG DVNRNVLCTS NPVESELHQQ AYEWAAKISE 

       190        200        210        220        230        240 
HLLPKTRAYA EIWLGEEKVE TTETEPVLGD SYLPRKFKTT VVIPPHNDVD VHANDLNFVA 

       250        260        270        280        290        300 
IAENGQLVGF NVLVGGGLAM THGDKSTYPR RAEDLGFIGL EHVLKVAEHV VTVQRDYGDR 

       310        320        330        340        350        360 
VNRKNAKTKY TLDRIGVDAF KSEVEQRVGV AFGPSRPYEF THRGDRFGWV EGIDGKHHLT 

       370        380        390        400        410        420 
LFIENGRLLD YPGKPLKTGV AEIAKVHKGD LRMTANQNLI IAGVAAEDKA QIEQLAREHG 

       430        440        450        460        470        480 
LLDNVTTQRK NSMACVSLPT CPLAMAEAER YLPTLVTHVE GILSKHGIAD DHIILRVVGC 

       490        500        510        520        530        540 
PNGCGRAMLA EAGLVGRGPG KYNLYLGGNT AGTRIPKLYL DNVAEAEILA ALDSLIGRWS 

       550        560        570 
VERNPGECFG DFVIRVGVVA EVKVSKTDFH A
A1S9I4 in FASTA format

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