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UniProtKB/Swiss-Prot entry A1CX69

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ATG1_NEOFI
Primary accession number A1CX69
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on January 23, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 15)
Name and origin of the protein
Protein name Serine/threonine-protein kinase atg1
Synonyms EC 2.7.11.1
Autophagy-related protein 1
Gene name
Name: atg1
ORFNames: NFIA_107120
From
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) [TaxID: 331117] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Neosartorya.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.1000046; PubMed=18404212 [NCBI, ExPASy, EBI, Israel, Japan]
Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M., Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
"Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus.";
PLoS Genet. 4:E1000046-E1000046(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
DS027685; EAW25221.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001267118.1; -.
3D structure databases
ModBase A1CX69.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0004674; Molecular function: protein serine/threonine kinase activity (inferred from electronic annotation from InterPro).
GO:0006914; Biological process: autophagy (inferred from electronic annotation from UniProtKB-KW).
GO:0006468; Biological process: protein amino acid phosphorylation (inferred from electronic annotation from InterPro).
GO:0015031; Biological process: protein transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000719; Prot_kinase_core.
IPR017441; Protein_kinase_ATP_bd_CS.
IPR017442; Se/Thr_pkinase-rel.
IPR008271; Ser_thr_pkin_AS.
IPR002290; Ser_thr_pkinase.
Graphical view of domain structure.
Pfam PF00069; Pkinase; 1.
Pfam graphical view of domain structure.
ProDom PD000001; Prot_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00220; S_TKc; 1.
SMART graphical view of domain structure.
PROSITE PS00107; PROTEIN_KINASE_ATP; 1.
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 4593469; -.
Other
ProtoNet A1CX69.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Autophagy; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Protein transport; Serine/threonine-protein kinase; Transferase; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   950  950     Serine/threonine-protein kinase atg1. PRO_0000317794
DOMAIN   6   311  306     Protein kinase. 
NP_BIND   12    20  9     ATP (By similarity). 
ACT_SITE   149   149        Proton acceptor (By similarity). 
BINDING   35    35        ATP (By similarity). 
Sequence information
Length: 950 AA [This is the length of the unprocessed precursor] Molecular weight: 103646 Da [This is the MW of the unprocessed precursor] CRC64: 19BA220961266A8D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSIGRYTRLD EIGRGSFATV YQGVHTKTRT YVAIKSVNLS KLNKKLKDNL SSEIHILKGL 

        70         80         90        100        110        120 
YHPHIVALID CHETTSHIHL VMEYCALGDL SLFIKRRDTL GDHRYTRDMI AKYPNPPGGA 

       130        140        150        160        170        180 
LNEVVVRHFL KQLASALKFL RDRNLIHRDI KPQNLLLCPS PSSYRSGVTQ VVPFKGSEDS 

       190        200        210        220        230        240 
FNPATGLESL PLLKIADFGF ARSLPATSLA ETLCGSPLYM APEILRYEKY DAKADLWSVG 

       250        260        270        280        290        300 
TVLYEMVVGK PPFRATNHVE LLRKIEKGED RIKFPEENPA SDEIKALIRA LLKRNPVERL 

       310        320        330        340        350        360 
NFPDFFENGV ITSPIPGLVA DDQPSIPRDP PADPETAEST PRPDSRSGAI VPGGTERERE 

       370        380        390        400        410        420 
VSYLPKGDTG LTQRPPSQNQ RFGTPPTTTH MRRIGSGDRP PSTPKELTPP MTYPQRPSAV 

       430        440        450        460        470        480 
SHATAPGRQE LVDRNAAFTA MERQRGRNTF SEGSPQTDRQ ADKLREERER AAQDVAFERD 

       490        500        510        520        530        540 
YVVVEKRAVE VNAFADELAH SPRIQGGISR GAQTGALSRR STVHGPTPLN PSPPQATVGK 

       550        560        570        580        590        600 
AMQVLSGRSR ADSMHNRQSS YERRYGQSPT SATSAISKAL NMASGRLFGM GFSPPLAITK 

       610        620        630        640        650        660 
GGRSPPLAYN PFPAYPAHGS LMIGDGAKNN VALDEDTKTV QILEECATRS DVVYGFAEVK 

       670        680        690        700        710        720 
YKQLVPLAPS VQTDPSSKGN LAGERENPDS ADGGLTVDAI VTLSEEALVL YVKALSLLAK 

       730        740        750        760        770        780 
SMDIAGAWWA RKNRGDGFGD SAMSRADGAS TLAGTRINNV VQWVRNRFNE VLEKGEFVRL 

       790        800        810        820        830        840 
KLIEAQKRLP PDHPSHPDNH SVGSSLGSGA SVDVVVSPGV SAEKLMYDRA LEMSRTAAIN 

       850        860        870        880        890        900 
ELTGEDLSGC EIAYVTAIRM LEAVLENGEV PRFGQGKDDT SKDSDKIVLD AVQAEERQVV 

       910        920        930        940        950 
IKLVSSIRSR LAALRKKLAI LAKRAPTPSA NVPSKMAPLN PVSVGATPPK
A1CX69 in FASTA format

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View entry in raw text format (no links)
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