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HAMAP: Burkholderia pseudomallei (strain 1106a) complete proteome

General information

Species:  Burkholderia pseudomallei (strain 1106a)
Species code: BURP0
Taxonomy: Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group (TaxID: 357348) [NEWT/ NCBI]
Description: Burkholderia pseudomallei is an opportunistic pathogen and a common cause of human pneumonia and fatal bacteremias in endemic areas. Clinical manifestations of B. pseudomallei infection, a disease known as melioidosis, vary greatly from an asymptomatic state, to benign pneumonitis, to acute or chronic pneumonia, or to overwhelming septicemia. Treatment of melioidosis can involve up to nine months of antibiotic therapy, and relapse of the disease is common. The latency period of the organism may vary from two days to 26 years. It is endemic in Southeast Asia and northern Australia, but has also been found in Africa, the Middle East, Europe, Central and South America. Besides humans, melioidosis can affect animals such as sheep, goats, horses, swine, dogs and cats. Transmission occurs by contact with contaminated soil and water, through skin abrasions or inhalation of dust. In northeastern Thailand, B.pseudomallei accounts for 20% of bacterial septicaemias (adapted from http://www.cdc.gov/ncidod/dbmd/diseaseinfo/melioidosis_g.htm).
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of BURP0 entries in the UniProt Knowledgebase: 7145 (373 in UniProtKB/Swiss-Prot + 6772 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    1106a
Genome structure:
• Chromosome I EMBL accession number CP000572 (circular; 3,988,455 bp) (download entry) (download Genome Reviews).
• Chromosome II EMBL accession number CP000573 (circular; 3,100,794 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] DeShazer D., Woods D.E., Nierman W.C. ;
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://msc.tigr.org/b_pseudomallei/burkholderia_pseudomallei_1106a/genbank.shtml
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid357348%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bpse_1106a
Pathema: http://pathema.tigr.org/tigr-scripts/Burkholderia/GenomePage.cgi?org=gbp1106a
 EBI Proteome Analysis page



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