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HAMAP: Burkholderia mallei (strain NCTC 10229) complete proteome

General information

Species:  Burkholderia mallei (strain NCTC 10229)
Species code: BURM9
Taxonomy: Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group (TaxID: 412022) [NEWT/ NCBI]
Description: Burkholderia mallei is the etiologic agent of glanders, a disease that is often fatal. Its natural reservoir are horses and other equines, but it can be occasionally transmitted to humans either by inhalation or through breaks in the skin. It is an obligate animal pathogen, with an intracellular localization. B. mallei is highly infectious as an aerosol and was used as a biological weapon in the American Civil War and in both World Wars. Unlike the related bacterium B.pseudomallei it is non-motile. One of its virulence factors has been identified as the type III secretion system, another as the newly characterized type VI (T6S). Strain NCTC 10229 will be used for comparative genomics.
Properties: Presence of flagella: No
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia (intracellular obligate)
Number of membranes: 2
Number of inteins:0
Statistics: Number of BURM9 entries in the UniProt Knowledgebase: 4957 (351 in UniProtKB/Swiss-Prot + 4606 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    NCTC 10229
Genome structure:
• Chromosome I EMBL accession number CP000545 (circular; 2,284,095 bp) (download entry) (download Genome Reviews).
• Chromosome II EMBL accession number CP000546 (circular; 3,458,208 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] DeShazer D., Woods D.E., Nierman W.C. ;
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://msc.tigr.org/b_mallei/burkholderia_mallei_10229/genbank.shtml
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=13943
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bmal_NCTC10229
Pathema: http://pathema.tigr.org/tigr-scripts/Burkholderia/GenomePage.cgi?org=gbm3
 EBI Proteome Analysis page



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