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NiceZyme View of ENZYME: EC 3.4.21.6

Official Name
Coagulation factor Xa.
Alternative Name(s)
Prothrombase.
Prothrombinase.
Stuart factor.
Thrombokinase.
Reaction catalysed
Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin
Comment(s)
  • Formed from the proenzyme factor X by limited proteolysis.
  • Scutelarin (cf. EC 3.4.21.60) has similar specificity.
  • Belongs to peptidase family S1.
Cross-references
Biochemical Pathways; map number(s)V1 ; V2
PROSITEPDOC00124
BRENDA3.4.21.6
PUMA23.4.21.6
PRIAM enzyme-specific profiles3.4.21.6
KEGG Ligand Database for Enzyme Nomenclature3.4.21.6
IUBMB Enzyme Nomenclature3.4.21.6
IntEnz3.4.21.6
MEDLINEFind literature relating to 3.4.21.6
MetaCyc3.4.21.6
UniProtKB/Swiss-Prot
P83370, FA10V_HOPST;  P82807, FA10V_NOTSC;  P81428, FA10V_TROCA;  
P00743, FA10_BOVIN;  P25155, FA10_CHICK;  P00742, FA10_HUMAN;  
O88947, FA10_MOUSE;  O19045, FA10_RABIT;  Q63207, FA10_RAT;  
Q4QXT9, FA10_TROCA;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
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