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NiceZyme View of ENZYME: EC 1.3.99.15

Official Name
Benzoyl-CoA reductase.
Alternative Name(s)
Benzoyl-CoA reductase (dearomatizing).
Reaction catalysed
Benzoyl-CoA + reduced acceptor + 2 ATP <=> cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate
Cofactor(s)
Iron-sulfur; Magnesium or manganese.
Comment(s)
  • Reduced methyl viologen can act as electron donor.
  • Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH(3) + acceptor + 2 ADP + 2 phosphate + H(2)O = hydroxylamine + reduced acceptor + 2 ATP.
  • In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.
Cross-references
BRENDA1.3.99.15
PUMA21.3.99.15
PRIAM enzyme-specific profiles1.3.99.15
KEGG Ligand Database for Enzyme Nomenclature1.3.99.15
IUBMB Enzyme Nomenclature1.3.99.15
IntEnz1.3.99.15
MEDLINEFind literature relating to 1.3.99.15
MetaCyc1.3.99.15
UniProtKB/Swiss-Prot
O87876, BCRA_THAAR;  O87875, BCRB_THAAR;  O87874, BCRC_THAAR;  
O87877, BCRD_THAAR;  

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