| Official Name |
|---|
| (S)-canadine synthase.
|
| Alternative Name(s) |
|---|
| (S)-tetrahydroberberine synthase. |
| (S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming). |
| Reaction catalysed |
|---|
| (S)-tetrahydrocolumbamine + NADPH + O(2) <=> (S)-canadine + NADP(+) + 2 H(2)O |
| Cofactor(s) |
|---|
| Heme-thiolate.
|
| Comment(s) |
|---|
- Catalyzes an oxidative reaction that does not incorporate oxygen into
the product.
- Oxidation of the methoxyphenol group of the alkaloid
tetrahydrocolumbamine results in the formation of the methylenedioxy
bridge of canadine.
- Formerly EC 1.1.3.36.
|
| Cross-references |
|---|
| PROSITE | PDOC00081 |
| BRENDA | 1.14.21.5 |
| PUMA2 | 1.14.21.5 |
| PRIAM enzyme-specific profiles | 1.14.21.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.21.5 |
| IUBMB Enzyme Nomenclature | 1.14.21.5 |
| IntEnz | 1.14.21.5 |
| MEDLINE | Find literature relating to 1.14.21.5 |
| MetaCyc | 1.14.21.5 |
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