| Official Name |
|---|
| Phenylacetone monooxygenase.
|
| Alternative Name(s) |
|---|
| PAMO. |
| Reaction catalysed |
|---|
| Phenylacetone + NADPH + O(2) <=> benzyl acetate + NADP(+) + H(2)O |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- NADH cannot replace NADPH as coenzyme.
- In addition to phenylacetone, which is the best substrate found to
date, this Baeyer-Villiger monooxygenase can oxidize other aromatic
ketones (1-(4-hydroxyphenyl)propan-2-one, 1-(4-hydroxyphenyl)propan-
2-one and 3-phenylbutan-2-one), some alipatic ketones (e.g. dodecan-
2-one) and sulfides (e.g. 1-methyl-4-(methylsulfanyl)benzene).
|
| Cross-references |
|---|
| BRENDA | 1.14.13.92 |
| PUMA2 | 1.14.13.92 |
| PRIAM enzyme-specific profiles | 1.14.13.92 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.92 |
| IUBMB Enzyme Nomenclature | 1.14.13.92 |
| IntEnz | 1.14.13.92 |
| MEDLINE | Find literature relating to 1.14.13.92 |
| MetaCyc | 1.14.13.92 |
| UniProtKB/Swiss-Prot |
|
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