ID   1.1.99.29
DE   Pyranose dehydrogenase (acceptor).
AN   PDH.
AN   Pyranose dehydrogenase.
AN   Pyranose-quinone oxidoreductase.
AN   Quinone-dependent pyranose dehydrogenase.
CA   (1) Pyranose + acceptor = 2-dehydropyranose + reduced acceptor.
CA   (2) Pyranose + acceptor = 3-dehydropyranose + reduced acceptor.
CA   (3) Pyranose + acceptor = 2,3-dehydropyranose + reduced acceptor.
CA   (4) A pyranoside + acceptor = a 3-dehydropyranoside + reduced acceptor.
CA   (5) A pyranoside + acceptor = a 3,4-dehydropyranoside + reduced acceptor.
CF   FAD.
CC   -!- A number of aldoses and ketoses in pyranose form, as well as
CC       glycosides, gluco-oligosaccharides, sucrose and lactose can act as a
CC       donor.
CC   -!- 1,4-benzoquinone or ferricenium ion (ferrocene oxidized by removal of
CC       one electron) can serve as acceptor.
CC   -!- Unlike EC 1.1.3.10, this fungal enzyme does not interact with O(2)
CC       and exhibits extremely broad substrate tolerance with variable
CC       regioselectivity (C-3, C-2 or C-3 + C-2 or C-3 + C-4) for
CC       (di)oxidation of different sugars.
CC   -!- D-glucose is exclusively or preferentially oxidized at C-3 (depending
CC       on the enzyme source), but can also be oxidized at C-2 + C-3.
CC   -!- The enzyme also acts on 1->4-alpha- and 1->4-beta-gluco-
CC       oligosaccharides, non-reducing gluco-oligosaccharides and
CC       L-arabinose, which are not substrates of EC 1.1.3.10.
CC   -!- Sugars are oxidized in their pyranose but not in their furanose form.
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