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ENZYME

ENZYME entry: EC 3.5.99.5

Accepted Name
2-aminomuconate deaminase
Reaction catalysed
(2Z,4E)-2-aminomuconate + H2O <=> (3E)-2-oxohex-3-enedioate + NH4(+)
Comment(s)
  • 2-aminomuconate is an intermediate in the bacterial biodegradation of nitrobenzene.
  • The enzyme has been isolated from several species, including Pseudomonas pseudocaligenes JS45, Pseudomonas fluorescens KU-7, Pseudomonas sp. AP3 and Burkholderia cenocepacia J2315.
  • The reaction is spontaneous in acid conditions.
Cross-references
BRENDA3.5.99.5
EC2PDB3.5.99.5
ExplorEnz3.5.99.5
PRIAM enzyme-specific profiles3.5.99.5
KEGG Ligand Database for Enzyme Nomenclature3.5.99.5
IUBMB Enzyme Nomenclature3.5.99.5
IntEnz3.5.99.5
MEDLINEFind literature relating to 3.5.99.5
MetaCyc3.5.99.5
Rhea expert-curated reactions3.5.99.5
UniProtKB/Swiss-Prot
P81593, 2AMD_PSEOLQ9KWS2, AMND_PSESPQ38M35, CNBH_COMTE

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