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ENZYME

ENZYME entry: EC 3.5.99.2

Accepted Name
aminopyrimidine aminohydrolase
Alternative Name(s)
thiaminase
thiaminase II
Reaction catalysed
  • 4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)
  • H2O + thiamine <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)
Comment(s)
Previously known as thiaminase II, this enzyme is involved in the regeneration of the thiamine pyrimidine from degraded products, rather than in thiamine degradation, and participates in thiamine salvage pathways.
Cross-references
BRENDA3.5.99.2
EC2PDB3.5.99.2
ExplorEnz3.5.99.2
PRIAM enzyme-specific profiles3.5.99.2
KEGG Ligand Database for Enzyme Nomenclature3.5.99.2
IUBMB Enzyme Nomenclature3.5.99.2
IntEnz3.5.99.2
MEDLINEFind literature relating to 3.5.99.2
MetaCyc3.5.99.2
Rhea expert-curated reactions3.5.99.2
UniProtKB/Swiss-Prot
B6TPF2, TENA2_MAIZEF4KFT7, TENAC_ARATHQ9ASY9, TENAE_ARATH
Q9SWB6, TENAE_SOYBNP25052, TENA_BACSUQ9K9G8, TENA_HALH5
A8KRL3, TENA_HELPXQ2FF32, TENA_STAA3Q2FWG0, TENA_STAA8
Q2YUL0, TENA_STAABQ5HEA5, TENA_STAACQ99SG3, TENA_STAAM
Q7A4F3, TENA_STAANQ6GEY1, TENA_STAARQ6G7L6, TENA_STAAS
Q7A0C8, TENA_STAAWO54496, TENA_STACTQ5HMC7, TENA_STAEQ
Q8CNK1, TENA_STAESQ4L7X6, TENA_STAHJQ49Z42, TENA_STAS1
Q08224, THI20_YEAST

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