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ENZYME

ENZYME entry: EC 3.5.2.17

Accepted Name
hydroxyisourate hydrolase
Alternative Name(s)
5-hydroxyisourate hydrolase
HIUHase
Reaction catalysed
5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)
Comment(s)
  • The reaction is the first stage in the conversion of 5-hydroxyisourate into (S)-allantoin.
  • This reaction will also occur spontaneously, but more slowly.
Cross-references
BRENDA3.5.2.17
EC2PDB3.5.2.17
ExplorEnz3.5.2.17
PRIAM enzyme-specific profiles3.5.2.17
KEGG Ligand Database for Enzyme Nomenclature3.5.2.17
IUBMB Enzyme Nomenclature3.5.2.17
IntEnz3.5.2.17
MEDLINEFind literature relating to 3.5.2.17
MetaCyc3.5.2.17
Rhea expert-curated reactions3.5.2.17
UniProtKB/Swiss-Prot
Q21882, HIUH1_CAEELQ92VB9, HIUH1_RHIMEO44578, HIUH2_CAEEL
Q92UG5, HIUH2_RHIMEO32142, HIUH_BACSUQ8YFU1, HIUH_BRUME
Q8G228, HIUH_BRUSUQ9A545, HIUH_CAUVCQ06S87, HIUH_DANRE
Q9RV69, HIUH_DEIRAQ8XB75, HIUH_ECO57P76341, HIUH_ECOLI
Q9KET9, HIUH_HALH5Q9CRB3, HIUH_MOUSEQ9I3J5, HIUH_PSEAE
Q8XXJ7, HIUH_RALN1Q98CI7, HIUH_RHILOQ4VYA5, HIUH_SALDU
Q8Z7Q6, HIUH_SALTIQ8ZQ52, HIUH_SALTYO74492, HIUH_SCHPO
Q8S3J3, HIUH_SOYBNQ9LVM5, TTHL_ARATH

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