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ENZYME

ENZYME entry: EC 3.3.2.2

Accepted Name
lysoplasmalogenase
Alternative Name(s)
alkenylglycerophosphocholine hydrolase
alkenylglycerophosphoethanolamine hydrolase
Reaction catalysed
  • 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O <=> a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine
  • 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine
Comment(s)
  • Lysoplasmalogenase is specific for the sn-2-deacylated (lyso) form of plasmalogen and catalyzes hydrolytic cleavage of the vinyl ether bond, releasing a fatty aldehyde and sn-glycero-3-phosphocholine or sn-glycero-3-phosphoethanolamine.
  • Formerly EC 3.3.2.5.
Cross-references
BRENDA3.3.2.2
EC2PDB3.3.2.2
ExplorEnz3.3.2.2
PRIAM enzyme-specific profiles3.3.2.2
KEGG Ligand Database for Enzyme Nomenclature3.3.2.2
IUBMB Enzyme Nomenclature3.3.2.2
IntEnz3.3.2.2
MEDLINEFind literature relating to 3.3.2.2
MetaCyc3.3.2.2
Rhea expert-curated reactions3.3.2.2
UniProtKB/Swiss-Prot
Q5ZU17, LYPGN_LEGPHP64838, LYPGN_MYCBOP9WG50, LYPGN_MYCTO
P9WG51, LYPGN_MYCTUQ3MHQ7, TM86A_BOVINQ8N2M4, TM86A_HUMAN
Q9D8N3, TM86A_MOUSEQ3T0W0, TM86B_BOVINQ8N661, TM86B_HUMAN
Q497J1, TM86B_MOUSEF1RMN2, TM86B_PIGB0BNF0, TM86B_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-