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ENZYME

ENZYME entry: EC 1.3.1.1

Accepted Name
dihydrouracil dehydrogenase (NAD(+))
Reaction catalysed
  • 5,6-dihydrouracil + NAD(+) <=> H(+) + NADH + uracil
  • 5,6-dihydrothymine + NAD(+) <=> H(+) + NADH + thymine
Comment(s)
  • The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.
  • Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli.
Cross-references
BRENDA1.3.1.1
EC2PDB1.3.1.1
ExplorEnz1.3.1.1
PRIAM enzyme-specific profiles1.3.1.1
KEGG Ligand Database for Enzyme Nomenclature1.3.1.1
IUBMB Enzyme Nomenclature1.3.1.1
IntEnz1.3.1.1
MEDLINEFind literature relating to 1.3.1.1
MetaCyc1.3.1.1
Rhea expert-curated reactions1.3.1.1
UniProtKB/Swiss-Prot
Q8X643, PREA_ECO57P25889, PREA_ECOLIQ8ZNL7, PREA_SALTY
Q8X645, PRET_ECO57P76440, PRET_ECOLIQ8Z5A6, PRET_SALTI
Q8ZNL8, PRET_SALTY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
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